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Product Name Anti-Calponin Antibody (Monoclonal, CP-93)Description Mouse IgG monoclonal antibody for Calponin, calponin 2 (CNN2)detection. Tested with WB, IHC-P, ICC in Human;chicken;turkey.No cross reactivity with other proteins.Host MouseTarget Species Chicken, Human, TurkeyApplication IHC-P, ICC, WBRecommendedDetectionSystemsWe recommend Enhanced Chemiluminescent Kit with anti-MouseIgG (EK1001) for Western blot, and HRP Conjugated anti-MouseIgG Super Vision Assay Kit (SV0001-1) for IHC(F).*Blocking peptide can be purchased. Contact us for moreinformationImmunogen Turkey gizzard calponinSpecificity No cross reactivity with other proteinsPack Size 100μg/vialCatalogNumberAb1011Background:Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. Itis specifically expressed in smooth muscle and binds calmodulin, actin, andtropomyosin. It is able to inhibit the ATPase activity of myosin and is thought to play arole in smooth muscle contraction. Calponin is a smooth muscle specific, actin-,tropomyosin- and calmodulin-binding protein though to be involved in some way in theregulation or modulation of contraction.
Gene Name CNN2Protein Name Calponin-2Gene Full Name Calponin-2Protein Function Thin filament-associated protein that is implicated in theregulation and modulation of smooth muscle contraction. It iscapable of binding to actin, calmodulin, troponin C andtropomyosin. The interaction of calponin with actin inhibits theactomyosin Mg-ATPase activity.SequenceSimilaritiesBelongs to the calponin family.Tissue Specificity Heart and smooth muscle.Uniprot ID Human(Q99439), Mouse(Q08093)Alternative Names Calponin-2|CNN2|Calponin2
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