Anti-Calponin Antibody (Monoclonal,CP -93)

Description

Product Name Anti-Calponin Antibody (Monoclonal, CP-93)
Description Mouse IgG monoclonal antibody for Calponin, calponin 2 (CNN2)
detection. Tested with WB, IHC-P, ICC in Human;chicken;turkey.
No cross reactivity with other proteins.
Host Mouse
Target Species Chicken, Human, Turkey
Application IHC-P, ICC, WB
Recommended
Detection
Systems
We recommend Enhanced Chemiluminescent Kit with anti-Mouse
IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse
IgG Super Vision Assay Kit (SV0001-1) for IHC(F).
*Blocking peptide can be purchased. Contact us for more
information
Immunogen Turkey gizzard calponin
Specificity No cross reactivity with other proteins
Pack Size 100μg/vial
Catalog
Number
Ab1011
Background:
Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. It
is specifically expressed in smooth muscle and binds calmodulin, actin, and
tropomyosin. It is able to inhibit the ATPase activity of myosin and is thought to play a
role in smooth muscle contraction. Calponin is a smooth muscle specific, actin-,
tropomyosin- and calmodulin-binding protein though to be involved in some way in the
regulation or modulation of contraction.

Gene Name CNN2
Protein Name Calponin-2
Gene Full Name Calponin-2
Protein Function Thin filament-associated protein that is implicated in the
regulation and modulation of smooth muscle contraction. It is
capable of binding to actin, calmodulin, troponin C and
tropomyosin. The interaction of calponin with actin inhibits the
actomyosin Mg-ATPase activity.
Sequence
Similarities
Belongs to the calponin family.
Tissue Specificity Heart and smooth muscle.
Uniprot ID Human(Q99439), Mouse(Q08093)
Alternative Names Calponin-2|CNN2|Calponin2

International:

May vary, we will contact you!