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Product Name Anti-Calmodulin Antibody (Monoclonal, 6D4)Description Mouse IgG monoclonal antibody for Calmodulin, calmodulin 1;calmodulin 2; calmodulin 3 (CALM1; CALM2; CALM3) detection.Tested with WB in chicken;rat. No cross reactivity with otherproteins.Host MouseTarget Species Chicken, RatApplication WBRecommended Detection SystemsWe recommends Enhanced Chemiluminescent Kit with anti-MouseIgG (EK1001) for Western blot, and HRP Conjugated anti-MouseIgG Super Vision Assay Kit (SV0001-1) for IHC(F).*Blocking peptide can be purchased. Contact us for more informationImmunogen Preparation of purified calmodulin from Dictyostelium discoideumconjugated to KLH.Specificity No cross reactivity with other proteinsPack Size 100μg/vialCatalog Number Ab1010
Background:Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly20 members have been found. Calmodulin contains 149 amino acids and has 4calcium-binding domains. Its functions include roles in growth and the cell cycle as wellas in signal transduction and the synthesis and release of neurotransmitters. Threecalmodulin genes(CALM1, CALM2, and CALM3) map to chromosomes 14q24-q31,2p21.1-p21.3, and 19q13.2-q13.3, respectively
Clonality MonoclonalClone Number 6D4Form LyophilizedContents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mgNaN3 as preservative. *carrier free antibody available upon request.Reconstitution Add 1ml of 1XPBS buffer (catalog # 1XPBS-001) will yield aconcentration of 100ug/ml.Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. Itcan also be aliquoted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.Purification Ascites
Application Details:Application Concentration* Tested SpeciesPredictedSpeciesAntigenRetrievalWestern blot 0.5μg/ml Chicken,rat
Protein Target:Gene Name CALM1; CALM2; CALM3Protein Name CalmodulinGene Full Name calmodulin 1; calmodulin 2; calmodulin 3Protein Function Calmodulin mediates the control of a large number of enzymes,ion channels, aquaporins and other proteins by Ca(2+). Amongthe enzymes to be stimulated by the calmodulin-Ca(2+)complex are a number of protein kinases and phosphatases.Together with CCP110 and centrin, is involved in a genetic
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