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Product Name AlphaDermMelanomaCatalog Number EP002Product Format 6,12, and 24 wellStorage 37°CGENERAL INFORMATIONAlphaDermMelanoma is a 3D skin cancer model derived epidermal keratinocytes, normal,human dermal fibroblasts and human malignant melanoma cells. This 3D skin cancermodel is manufactured in a GMP lab. This model will enable researchers to a betterunderstand the molecular and cellular mechanisms involved in the progression ofcutaneous melanoma. These 3D models have been cultured to form a multilayered, highlydifferentiated epidermis with melanoma cells at various stages of CM malignancy. Atdifferent stages of the culture, the tissue exhibits radial growth phase (RGP), verticalgrowth phase (VGP), or metastatic melanoma phenotype. The 3D model parallels theprogression of melanoma in vivo, thus providing a valuable tool to study, understand, anddevelop preventive and therapeutic treatments for one of the most serious cutaneousmalignancies.This model can be used for, but not limited to those applications1) Tumor Invasion2) Anti- Melanoma drug screening.
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